孙慧

作者: 时间:2023-10-09 点击数:

   

      孙慧 103372.jpg

孙慧  博士,教授,硕士生导师     

 

环境科学与工程学院

广州大学

广州大学城外环西路230号,510006

Tel.020-39366943

E-mailesesunhui@gzhu.edu.cn

 

教育背景

 

2006年毕业于香港大学化学系,获博士学位

 

2002年毕业于南开大学化学系,获硕士学位

 

1994年毕业于武汉大学环境科学系,获学士学位

 

工作经历

 

1.     2010/10-至今,     广州大学,环境科学与工程学院,教授

 

2.     2006/08-2010/09  香港大学,化学系,博士后,

 

研究方向

 

环境功能材料以及环境原位检测技术研究。曾主持国家自然科学金基金4,教育部重点科技技术1项,广东省自然科学金基金1项,广州市科技计划项目2项,香港大学博士后基金1项,作为主要研究人员参与完成多项香港特别行政区创新科技基金、广东-香港技术合作基金、香港大学基础研究种子基金以及香港大学应用研究种子基金的科研工作。在本研究领域具有较高影响因子的J. Hazard. Mater., Sci..Total Environ., Biosens. Bioelectro.,Chemosphere, Trends Anal. Chem., Sens. Actaut. B  等杂志发表学术研究论文60 余篇,曾参与《Encyclopedia of Sensors,Microfluidic Chip-Capillary Electrophoresis Devices》著作编写,获得美国及中国专利共7 项。

 

主持科研项目

 

1. 家自然科学基金项目22376041基于聚集诱导发射-光子晶体复合材料的“双模式”可视化及远程监测放射性核素平台的构建2024-2027

2. 家自然科学基金项目21876033 光子晶体-离子印迹共价有机骨架材料在放射性核素等重金属富集分离和检测中的应用研究2019-2022

3. 国家自然科学基金项目21477026基于离子印迹与识别的重金属离子荧光光纤传感器的研究2015-2018

4. 国家自然科学基金项目2110701821107018,基于分子印迹微流控CE系统的空气羰基化合物分析的研究2012-2014

5. 教育部科学技术研究重点项目212129:空气中微量气、固态醛酮化合物测定的芯片技术研究2012.1-2014.12

6. 广东省自然科学基金项目2014A030313525大气PM2.5中羰基化合物的分子识别及微流控芯片监测系统研究2015-2018

7. 广州市科技计划项目2023A03J0035:矿山废水中放射性核素on-site在线检测及资源回收的“多功能”平台研究,2023-2025

8. 广州市科技计划项目201504291741356:雾霾中醛酮类污染物的快速检测系统研究2016-2019

9. 香港大学博士后项目:基于分子印迹和微流控技术的压电传感器在环境和临床中的应用2007-2010

 

论文

 

1. A. Q. Cui, X..Y. Wu, J. B. Ye, G. Song, D..Y. Chen, J. Xu, Y. Liu, J. P. Lai*, H. Sun* Two-in-oneDual-Function Luminescent MOF Hydrogel for Onsite Ultra-Sensitive Detection and Efficient Enrichment of Radioactive Uranium in Water, J. Hazard. Mater. 2023, 448: 130864.

2. X. Y. Wu, A. Q. Cui, J. B. Ye, G. Song, Y. N. Wu, Y. X. Wu, J. P. Lai*, H. Sun*; Novel biocompatible and sensitive visual sensor based on aggregation-induced emission for on-site detection of radioactive uraniumin water and live cell imaging, Sci..Total Environ., 2023, 858159796.

3. Y. N. Wu, X. Y. Wu, Y. Q. Liang, J. Yu Zeng, Y. X. Wu, J. P. Lai*, H. Sun*; A Strategy of Fluorescence-Visualization Dual Channelfor Highly Sensitive and Rapid Detection of Phosphate Biomarkers Based on Stimulus-Responsive Infinite Coordination Polymers, Sens. Actuat. B: Chem., 2022, 370132366.

4.  Qingda Huang, Caihua Lv, Xiaolin Yuan, Miao He, Jiaping Lai, Hui Sun*, A novel fluorescent optical fiber sensor for highly selective detection of antibiotic ciprofloxacin based on replaceable molecularly imprinted nanoparticles composite hydrogel detector. Sensors and Actuators B: Chemical 2021, 328, 129000

5. Y. Q. Liang, X. Y. Wu, J. Y. Zeng, Y. N. Wu, J. P. Lai*, H. Sun*, A novel fluorescence ratio probe based on dual-emission carbon dots for highly selective and sensitive detection of chlortetracycline and cell imaging. Anal. Bioanal. Chem. 2022, DOI:10.1007/s00216-022-03908-9.

6. X. L. Yuan, X. Y. Wu, M. He, J. P. Lai *, H. Sun*, A ratiometric fiber optic sensor based on CdTe QDs functionalized with glutathione and mercaptopropionic acid for on-site monitoring of antibiotic ciprofloxacin in aquaculture water. Nanomater. 2022, 12: 829.

7. J. Y. Zeng, Y. Q. Liang, Y. N. Wu, X. Y. Wu, J. P. Lai *, H. Sun*, Synthesis and application of novel N, Si-carbon dots for the ratiometric fluorescent monitoring of the antibiotic balofloxacin in tablets and serum, RSC Adv., 2022, 12, 2958529594.

8. Liu Yang-Yang, Gu Hang, He Jia-Hua, Cui An-Qi, Wu Xiao-Yi, Lai Jia-Ping, Sun Hui. Rapid screening of butyl paraben additive in toner sample by molecularly imprinted photonic crystal. Chemosensors, 2021, 9(11): 314.

9.  J. H. He, J. W. Liu, Y. Y. Liu, Z. X. Liyin, X. Y. Wu, G. Song, Y. Y. Hou, R. X. Wang, W. F. Zhao* and H. Sun*, Trace carbonyl analysis in water samples by integrating magnetic molecular imprinting and capillary electrophoresis. RSC Adv. 2021,11: 32841.

10. Wu Wei-Zhen, Wu Xiao-Yi, He Miao, Yuan Xiao-Lin, Lai Jia-Ping*, Sun Hui*. A novel carbon dot/polyacrylamide composite hydrogel film for reversible detection of the antibacterial drug ornidazole. RSC Adv., 2021, 11(37): 22993-23001.

11. Siyang Fang, Yangyang Liu, Jiahua He, Liuqing Zhang, Zhengxi Liyin, Xiaoyi Wu, Hui Sun*, Jiaping Lai, Determination of aldehydes in water samples by coupling magnetism-reinforced molecular imprinting monolith microextraction and non-aqueous capillary electrophoresis.  Journal of Chromatography A, 2020, 1632, (22) 461602  

12. Yi Zhang, Zhenkai Jin, Qingsong Zeng, Yanmei, Huang, Hang Gu, Shili Chen, Jiahua He, Yangyang Liu, Hui Sun*, Jiaping Lai, Field Visual Inspection of Illegal Additive in Wine Based on Functional Photonic Crystal Sensor, Microchimia Acta, 2019,186 (11).

13.  Yunling Li, Hui Sun*, Jiaping Lai, Xiangyang Chang, Ping Zhang, Shili Chen Determination of carbonyl pollutants adsorbed on ambient particulate matter of type PM2.5 by using magnetic molecularly imprinted microspheres for sample pretreatment and capillary electrophoresis for separation and quantitation, Microchimica Acta 2018, 185 (2):122-134. 

14. Mengxia Huang, Jiaping Lai, Hui Sun* Weizhen Wu. A simple, highly selective and ultra-sensitive "off-on-off" fluorescent chemosensor for successive detection of aluminum ion and phosphate in water samples. Microchemical journal, 2019, 151.

15. Shili Chen, Hui Sun*, Zhenjian Huang, Siyang Fang, Jiahua He, Yangyang Liu, Jiaping Lai, Yi Zhang, Zhenkai Jin, Visual detection of anesthetics in fish based on inverse opal photonic crystal sensor, RSC Advances, 2019, 9 (29): 16831 - 16838.

16. Mengxia Huang, Caihua Lv, Qingda Huang, Jiaping Lai, Hui Sun* A novel and fast responsive turn-on fluorescent probe for the highly selective detection of Cd2+ based on photo-induced electron transfer. RSC Advances  2019,9 (62): 36011-36019.

17. Weizhen Wu, Mengxia Huang, Qingda Huang, Caihua Lv, Jiaping Lai, Hui Sun*, Molecularly Imprinted Photonic Hydrogelsfor Visual Detection of Methylanthranilate in Wine. Chin. J. Anal. Chem., 2019,  47 (9) : 1330-1336. 

18. Siyang Fang, Shili Chen, Jiahua He, Hao Wang, Lisi Shen, Yangyang Liu, Hui Sun*, Jiaping Lai*, Determination of carbonyls in ambient PM2.5 by coupling dummy template imprinting technology and high performance liquid chromatography. Chin. J. Chromatography,  2019.37 (6): 634-643

19. Shili Chen ; Zhenjian Huang; Siyang Fang; Jiahua He; Yangyang Liu; Jiaping Lai , Hui Sun*, Molecular Imprinted Photonic Crystal Sensor For The Rapid and Visual Detection of Benzocaine In Fish, Key Engineering Materials. (ISSN: 1662-9795), 2019803,129-133.

20. Hui Sun, Jiaping Lai, Dongsheng Lin, Xuexia Huang, Yunling Li, A novel fluorescent multi- functional monomer for preparation of silver ion-imprinted fluorescent on-off chemosensor. Sens. Actuat. B, 2016, 224: 485-491.

21. Yanhui He, Jiaping Lai, Hui Sun*, Zhiming Chen, Sheng Lan. A fast, sensitive and stable fluorescent fiber-optic chemosensor for quantitative detection of Fe3+ in real water and HepG2 living cells. Sens. Actuat. B, 2016, 225:405-412.

22.  Fashuo Shan, Jiaping Lai, Hui Sun*, Ping Zhang, Chong Luo, Yanhui He, Huanran Feng. A facile, fast responsive and highly selective mercury(II) probe characterized by the fluorescence quenching of 2,9-dimethyl-1,10-phenanthroline and two new metal-organic frameworks. RSC Advances, 2016, 6, 66215-66223.

23. Hui Sun, Jiaping Lai, Fang Chen, Derong Zhu. Molecularly imprinted microspheres synthesized by a simple, fast and universal suspension polymerization for selective extraction of topical anesthetics benzocaine in human serum and fish tissues. Anal. Bioanal. Chem., 2015, 407: 1745-1752.

24. Jiaping Lai, Yue Zuo, Hui Sun*, Ying Yu. Hydrophilic molecularly imprinted microspheres functionalized with amino and carboxyl groups for highly selective recognition of human hemoglobin in aqueous solution, RSC Advances2015,5(63): 51392-51398.

25.  Hui Sun, Jiaping Lai*, Yingsing Fung, Simultaneous determination of gaseous and particulate ambient carbonyls by coupling micellar electrokinetic capillary chromatography with molecular imprinting solid-phase extraction. J. Chromatogr. A, 2014, 1358: 303-308. 

26. Jiaping Lai, Fang Chen, Hui Sun*, Li Fan, Yue Zuo. Molecularly imprinted microspheres for anti-cancer drug aminoglutethimide: synthesis, characteri- zation and solid-phase extraction application in human urine sample. J. Sep. Sci., 2014, 37:1170-1176.

27. Dongsheng Lin, Jiaping Lai, Hui Sun*, Zhou Yang, Yue Zuo. A turn-on fluorescein spirolactam derivative as a high selective fluorescence probe for detection of silver ion (I) in water. Anal. Methods, 2014, 6: 1517-1522.

28.  Jiaping Lai, Li Xie, Hui Sun*, Fang Chen. Synthesis and evaluation of molecularly imprinted polymeric microspheres for highly selective extraction of an anti-AIDS drug emtricitabine. Anal. Bioanal. Chem., 2013,405: 4269-4275.

29. Derong Zhu, Hui Sun*, Hongju Liu, Minghua He, Comparison of Determination Methods for Phthalates by Liquid-Phase Microextraction Coupled Gas Chromatograph-Mass spectrometry. Chin.  J. Anal. Chem., 2013,41 (10):1582-1586.

30. Hui Sun, Kwokman Lau, Yingsing Fung*, A new capillary electrophoreSis buffer for determining organic and inorganic anions in electroplating bath with surfactant additives, J. Chromatogr. A, 2010, 1217: 3244-3250. 

31. Hui Sun, Zhou Nie, Yingsing Fung*. Determination of free bilirubin and its binding capacity by HSA using a microfluidic chip-capillary electrophoresis device with a multi-segment circular-ferro fluid-driven micromixing injection. Electrophoresis, 2010, 31(18): 3061-3069. 

32. Hui Sun, Yingsing Fung. DNA biosensor based on quartz crystal microbalance and polymerase chain reaction for detecting E. Coli. in environmental water. Biosens. Bioelectron., 2009, 24:1405-1411. 

33. Hui Sun, Zhihong Mo, Jacqueline Tszshan.Choy,Derong Zhu, Yingsing Fung*. Development of piezoelectric quartz crystal sensor array for sensing taste-causing compounds in food. Sens. Actuat. B, 2008, 131: 148-158.

34. Hui Sun, Kingyee Chan, Yingsing Fung*. Determination of gaseous and particulate carbonyls in air by gradient-elution micellar electrokinetic capillary chromatography. Electrophoresis, 2008, 29: 3971-3979.

35. Hui Sun, Yingsing Fung*, Flow analysis coupled with PQC/DNA biosensor for assay of E. coli based on detecting DNA products from PCR amplification. Biosens. Bioelectron., 2006, 22: 506-512.

36. Hui Sun, Yingsing Fung*. Piezoelectric quartz crystal sensor for rapid analysis of piriicarb residues using molecularly imprinted polymers as recognition elements. Anal. Chim. Acta, 2006, 576: 67-76.

37. Hui Sun, Youyu Zhang, Shihui Si, Derong Zhu, Yingsing Fung*. Piezoelectric quartz crystal (PQC) with photochemically deposited nano-sized Ag particles for determining cyanide at trace levels in water. Sens. Actuat. B-Chem. 2005, 108: 925-932. 

 

著作

 

1. Hui Sun, Yingsing Fung, (Chapter 6) sample cleanup and analyte enrichment -integrating MIP/SPE with ME/MC-CE device to enhance sample cleanup and multi-dimension analyte enrichment for hourly determination of atmospheric carbonyl compounds, Microfluidic Chip-Capillary Electrophoresis (MC-CE) Devices -Integrating techniques to achieve intended applications, CRC press, 2015

2. Yingsing Fung, Youyu Zhang, Shihui Si, Hui Sun and Shouzhuo Yao, DNA Piezoelectric Quartz Crystal Biosensor, Encyclopedia of Sensors, American Scientific Publishers, CA, USA. 2006

 

授权专利

 

1. 孙慧; 崔安琪; 邬晓忆; 叶俊彬; 赖家平; 一种镧系发光MOF水凝胶的制备方法及应用ZL202210905183.6

2. 赖家平; 冯焕然; 单法硕; 孙慧; 一种水体中二/三价铁离子的检测方法,ZL201811631214.3

3. 赖家平; 曾嘉榆; 梁玉琪; 孙慧; 硼硫掺杂碳量子点及其制备方法和应用,ZL202210542443.8

4. Yingsing Fung, Hui Sun, Zhihong Mo, Derong Zhu, Tszshan Jacqueline Choy, Yinyee Lee, Electronic Tongue Sensor, 2011.8, US Patent, 8,004,152B2

5. 冯应升; 孙慧; 莫志宏; 朱德荣; 蔡紫珊; 李贤意. 电子舌传感器,2013.4, 中国, ZL200880107103.0

6. 陈永亨; 张平; 陈绮洁; 姚焱; 吴颖娟; 黄雪夏; 李祥平; 孙慧. 一种以铅锌矿冶炼废水为原料制备碘化亚铊的方法,2014, 中国, ZL201410114415.1

7. 赖家平,左悦,林东升,何燕惠,孙慧 一种荧光多功能单体及其合成方法与应用 ZL201510217322.6

 

研究生及本科生培养

 

多次获本科课堂教学优秀一等奖二等奖;曾被评为最受学生欢迎的老师

 


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